olecular diagnostic techniques that can help diagnose hemoglobin disorders such as hemoglobinopathies and thalassemias include a) biochemical separation, identification, and quantification of mixture components b) separation of macromolecules and their fragments, based on their size and charge c) DNA amplification, hybridization, and nucleotide sequencing d) The use of specific monoclonal antibodies

Answers

Answer 1

Answer:

The correct answer is - a) biochemical separation, identification, and quantification of mixture components.

Explanation:

Most hemoglobin disorders can be diagnosed by molecular diagnostic techniques such as protein-based techniques like electrophoresis and chromatography. Protein-based methods can diagnose early thalassemia disorders and hemoglobinopathies but in the case of α-thalassemia may be masked in the presence of β-thalassemia.

Molecular genetic testing plays a very important role in the biochemical separation of molecules or components, identification, and quantification of individuals carrying thalassemia and hemoglobinopathies traits and other hemoglobin disorders.


Related Questions

What is a working copy of DNA that leaves the nucleus of the cell? And is read by organelles called that connect amino acids together to make proteins

Answers

Answer:

Messenger RNA

Explanation:

Why were fruit flies chosen?

Answers

Answer:

19099

Explanation:

we just make sure about my dear friend

Answer:

d

Explanation:

In both prokaryotes and eukaryotes, initiation of translation usually

a. begins immediately upstream of a Shine-Dalgarno sequence.
b. requires the action of release factors, which cause the small and large subunits of a ribosome to associate with one another.
c. requires the action of initiation factors.
d. begins at a UAG codon downstream of the 5’ UTR of an mRNA molecule.
e. begins only after ubiquitin has been added to the mRNA molecule to be translated.

Answers

Answer:

c. requires the action of initiation factors.

Explanation:

Transcription is the process by which a fragment of DNA (e.g., a gene) is used as a template to create a complementary RNA molecule, usually a messenger RNA (mRNA) molecule which is then used to synthesize a polypeptide chain (i.e., a protein) in the ribosomes by a process called translation. Initiation factors are proteins capable of binding the ribosome in order to promote (or prevent) the initiation of translation. In prokaryotic cells, the initiation factors IF1, IF2 and IF3 (IFs) are required for the selection and the quantity of the protein produced. In eukaryotic cells, translation initiation occurs when an initiator tRNA, 40S, and 60S ribosomal subunits are assembled by eukaryotic initiation factors (eIFs) into an 80S ribosome on the initiation codon of an mRNA. In eukaryotes, translation initiation is promoted and regulated by at least twelve eIFs (e.g., eIF1, eIF1A, eIF2, eIF3, eIF4, eIF5, eIF5A, eIF5B, etc) which are composed of many polypeptides.

A relationship in which one species kills and consumes another species is known as
predation.
parasitism.
commensalism.
mutualism.

Answers

Predation is a biological interaction where one organism, the predator, kills and eats another organism, its prey

A relationship in which one species kills and consumes another species which is called as the Predation. So, the correct option is A.

What is Predation?

Predation is defined as the relationship in which one species kills and consumes another species. It is a type of community relationship in which organisms of one species, also known as predator, consume the tissues of organisms of another species, called prey, which means killing the prey and killing all or most of the prey organisms.

Herbivores are explained as predators in which the prey organism is a plant.  Predation is described as the natural way of transferring the energy fixed by plants to higher trophic such as snake eating a frog tiger killing and eating a deer.

Therefore,  the correct option is A.

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When a new volcanic island is formed, what type of succession would you see? Describe some things that might happen.

Answers

Answer:

primary succession

Explanation:

you would start to see bacteria, fungi and lichens grow as the pioneer species.

help me out with this​

Answers

I don't know dinosaur I'm sorry


show the outcome of the offspring genotypes and their
phenotypic ratio if parental genotype WWPP was cross bred with wwpp
(8)​

Answers

Answer:

Ww Ww Pp Pp Wp Pw Wp Pw

Explanation:

When curare, a neuromuscular poison, is dropped onto an isolated muscle-nerve preparation in a laboratory, the muscle does not contract when the nerve is stimulated, even though neurotransmitter is released from the nerve cell. Why does this happen

Answers

Answer:

Explanation:

Whenever the nerve terminal's action potential depolarizes, calcium enters the cell through the channels. Calcium allows acetylcholine (ACh) to be released more easily.  These ACh molecules subsequently circulate into the synaptic cleft and attach to the motor end-plate of the nicotinic cholinergic receptors. Acetylcholine molecules connect to nicotine ion-channel receptors present on cell membrane the of muscle cells, enabling the ion channels to open. Calcium ions then enter the muscle cell, kicking off a series of events that eventually result in muscular contraction.

Curare is a kind of neuromuscular relaxant blocker that is non-depolarized in nature. Nondepolarizing muscle relaxants work as competitive agonists, binding to ACh receptors but failing to activate ion channels. As a result, they inhibit ACh from bonding, preventing the development of endplate potentials and inducing muscle paralysis.

Which of the following techniques employs a probe consisting of a labeled, single-stranded DNA of known sequence that can find and bind to a complementary sequence present in a large sample of different DNA sequences?

a. DNA hybridization
b. RFLP
c. PCR
d. DNA sequencing

Answers

Answer:

Explanation:

PCR

Scientific names of organisms consist of___________.
plz i need it

Answers

The answer is:
genus and species

Write any two demerits of local system of measurement.​

Answers

Answer:

) It's easier for younger people to change than older people. (3) It ignores, and devalues cultural differences, expressions, and idioms, based on imperial measurements. For example: can a British pub be truly British without "Pints of beer"? - "Half a litre of beer" doesn't quite have the same ring to it!

1. cannot be used in international trade.

2. cannot be used in scientific experimemts.....

Recalling Darwin's Theory
QUICK CHECK
Determine whether each statement is true or false according to Darwin's theory.
Organisms within a population must compete for resources to survive.
The least-equipped organisms may not survive.
Over time, inheritance of beneficial variations can change the entire species.
All organisms in a population are equally equipped for survival.
Some organisms will outcompete others.
DONE

Answers

Answer: True.

True.

False

False

True

Explanation:

• Organisms within a population must compete for resources to survive. - True

• The least-equipped organisms may not survive. - True

• Over time, inheritance of beneficial variations can change the entire species. - False

• All organisms in a population are equally equipped for survival. - False

• Some organisms will outcompete others. - True

Accordingly to Charles Darwin’s theory of evolution, evolution occurs through natural selection. There are variations on the physical characteristics shown by the individuals in a specie.

The individuals that are more likely to survive are the ones that have the characteristics which are best suited to their environment and are therefore, more likely to survive.

10. What processes found at hot spots will help form the following rocks? (4 points)
A. Metamorphic rocks
B. Igneous rocks
It’s not multiple choice I need a answer for both

Answers

Answer:

metamorphic rock

Explanation:

metamorphic rock simply means that the rocks have been geophysically altered. heat is always a primary source for alteratino of rock so the heat ofmolten rock generated by hot spots can easily cause an abundance of metamorphic rocks within the system

hey loves, im helping a friend do an assignment because they’re sick and in super confused.

Answers

Answer:

See below

Explanation:

Sandstone deposited, limestone deposited, shale deposited, limestone deposited, shale deposited, erosion, igneous rock intrusion, fault along XY

55 POINTS PLS HELP


One statement is an example of a scientific observation. Another statement is an example of a scientific explanation. Identify the correct statement for each category to illustrate how scientific explanations are inferred from scientific observations.

Cloning has the potential to
significantly benefit a great many
people, so it should not be
considered immoral or risky.

A scientist thinks that he might
find serious inconsistencies in the
fossil record if he conducts an
excavation in a new location.

The rocks present in western Africa
and eastern South America formed
at the same place and at the
same time.

Even if modern organisms are
found in ancient portions of the
fossil record, this wouldn't challenge
the theory of evolution in any way.

The cloning of organisms is an
exciting area of study, and more
resources should be be devoted
to it.

The age, type, and composition of
ancient rocks in western Africa are
nearly identical to the age, type,
and composition of rocks in
eastern South America.

Answers

Answer:

2, 4, and 5 refers to scientific revolution while on the other hand, the remaining statements shows scientific observation.

Explanation:

Cloning has the potential to  significantly benefit a great many  people, so it should not be  considered immoral or risky is refers as scientific observation.

A scientist thinks that he might  find serious inconsistencies in the  fossil record if he conducts an  excavation in a new location is refers scientific explanation because explanation is needed for it.

The rocks present in western Africa  and eastern South America formed  at the same place and at the  same time is scientific observation because the scientists takes the data.

Even if modern organisms are  found in ancient portions of the  fossil record, this wouldn't challenge the theory of evolution in any way is refers to scientific explanation.

The cloning of organisms is an  exciting area of study, and more  resources should be be devoted  to it so it is refers as scientific explanation.

The age, type, and composition of  ancient rocks in western Africa are  nearly identical to the age, type,  and composition of rocks in  eastern South America is scientific observation which is taken by the scientist through research.

Monocercomonoides are a genus of single-celled organisms that live as parasites in the guts of small animals. They lack mitochondria, but other evidence shows them to be most closely related to members of the excavates. Looking at the tree for eukaryotes, what can you conclude about the Monocercomonoides?
A. Since excavates are eukaryotes, it is extremely unusual for one of them to lack mitochondria.
B. Excavates branched off before the evolution of mitochondria, so the absence is not surprising.
C. Since they are parasites of animals, they should be placed within the opisthokont branch of the tree.
D. A phylogenetic tree reflects evolutionary relationships, so they should be placed within the excavates.
E. Their lineage likely had mitochondria but lost them at some point.

Answers

Answer: A. Excavates branched off before the evolution of mitochondria, so the absence is not surprising.

C. Since they are parasites of animals, they should be placed within the opisthokont branch of the tree.

E. Their lineage likely had mitochondria but lost them at some point.

Explanation:

Based on the information given, the conclusion that can be made about the monocercomonoides include:

• Excavates branched off before the evolution of mitochondria, so the absence is not surprising.

• Since they are parasites of animals, they should be placed within the opisthokont branch of the tree.

• Their lineage likely had mitochondria but lost them at some point.


2. What is another word for sound quality?
timbre
interference
overtone
acoustics

Answers

Answer:

acoustics timbre are other words for sound quality

Answer:

I would say timbre.

Explanation:

I hope this helps u

When looking at the genome of an uncultured microbe, the discovery of a(n) ________-encoding gene provides evidence that the microbe can grow in the presence of oxygen. Multiple Choice reductase catalase dehydrogenase ABC-type transporter

Answers

Answer:

i dont know man

Explanation:

i just need brainly points man sorry

Catalase is an enzyme observed in organisms exposed to oxygen. This enzyme acts to catalyze the conversion of hydrogen peroxide (H2O2) into water and oxygen.

The discovery of a CATALASE-encoding gene provides evidence that the microbe can grow in the presence of oxygen.

Catalase is a key enzyme that protects the cell from oxidative stress damage.

Catalase acts together with the enzyme superoxide dismutase, which in turn catalyzes the formation of H2O2 from superoxide radicals.

In conclusion, the discovery of a CATALASE-encoding gene provides evidence that the microbe can grow in the presence of oxygen.

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Which of the following findings would lead you to determine that an infant's airway is open

Answers

Answer:

blowing air into his/her mouth and checking for an increase in the thoracic region........I GUESS

•. otal genomic structure of an organism inherited from parents is known as -
a) Gene
b) Allele
c) Phenotype
d) Genotype​

Answers

I think the answer is a sorry if I get it wrong

Q.#11. Mitochondria and chloroplasts share structural and functional similarities. Which of the following
do both these organelles have in common?
A. generate ATP
B. create complex molecules
C. contain their own DNA D. are found inside vacuoles
E. are surrounded by a cell wall​

Answers

Answer:

b.

Explanation:

Both mitochondrial membrane and thylakoid of chloroplast possess phosphorylation for energy production in the form of ATP.

definition of human rights

Answers

Answer: a right that is believed to belong justifiably to every person.

Explanation:

Answer:

Human rights are standards that allow all people to live with dignity, freedom, equality, justice, and peace. Every person has these rights simply because they are human beings.

Explanation:

Human rights are rights inherent to all human beings, regardless of race, sex, nationality, ethnicity, language, religion, or any other status. Human rights include the right to life and liberty, freedom from slavery and torture, freedom of opinion and expression, the right to work and education, and many more.


If Tyler does not eat a diet that includes essential amino acids, his cells will not be able to build

Answers

Answer:

Essential amino acids are constituents for proteins associated with energy production, growth, nutrient absorption, and immunity. Thus, if Tyler does not take a diet having essential amino acids, he will not be able to build some kinds of proteins as amino acids are building blocks for proteins.

ba kiểu truyền tín hiệu của tế baò

Answers

Repost it in English please

A 5'6", 210 pound, 64 year old man had a physical exam prior to his retirement for corporate work. His blood pressure was greater than 180/115 mmHg on three separate days (normal blood pressure is 120/80). Further examination showed normal to low plasma renin activity, elevated systemic vascular resistance (SVR), x-ray showed left ventricular hypertrophy and retinal hemorrhage and cardiac output was 7.2 L/min (normal is 3.5 to 5.5 L/min). Recommended therapy was weight reduction to his ideal weight, low salt diet. If these life style changes did not change his condition the following medication will be started in the following order: oral diuretics progress to beta blockers and then to a vasodilator.

Required:
a. What is the diagnosis for this individual?
b. Why is it suggested that the patient go on a low sodium diet?
c. Explain the site and mechanism of action of each of these prescribed medications.

Answers

Answer:

Explanation:

a.

The individual should be diagnosed for hypertension or high blood pressure.

b.

It is recommended that the patient should take low sodium diet because when sodium or salt enters the blood stream it increases the amount of water or fluids in the blood stream that leads to rise in blood pressure. The blood pressure increases if we take high salt diet due to which arterioles constrict.

c.

Diuretics- Diuretics are the first recommended therapy in treating hypertension. Diuretics such as thizides , pottasium sparing agents. Thiazide acts on distal convoluted tubule that inhibits Na+ and Cl - symporter. Diutetic removes water from body as urine and loss of salt.

Beta blockers - These are antagonists. They block the beta receptors found on the target cell membrane. Beta blockers slows down blood pressure. Atenolol is the beta blocker used for hypertension.

Alpha1 blocker - alpha 1 receptors helps in smooth muscle contraction and vasoconstriction. Vasodilator increases blood flow in the body that are devoid of oxygen that helps to reduce blood pressure.

angiotensin converting enzyme inhibitor - blocks angiotensin converting enzyme that prevents converting angiotensin I to angiotensin II and increases bradykinin levels in the body. These inhibitors helps in lowering blood pressure.

It’s biology someone help

Answers

Ecosystem and a pond

A young plant growing from a seed is called a ...

Answers

Answer:

the answer is seedling

In the SDS-PAGE (sodium dodecylsulfate - polyacrylamide gel electrophoresis) method, separation takes place on the basis of:_____________

a. charge only, because all particles have different charges, but the same mass.
b. the sieving action of the gel, because all particles have the same charge, but different masses.
c. the sieving action of the gel, because all particles have approximately the same charge/mass ratio, but different masses.
d. the chemical nature of the buffer used as the electrolyte.

Answers

Answer:

B

Explanation:

Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) is a method of separating molecules based on the difference of their molecular weight.

What is a working copy of DNA and is read by organelles called?

Answers

Answer:

Working copy of DNA is RNA (Ribonucleic acid)

The nucleus controls all of the cell’s activities, such as growth and metabolism, using the DNA’s genetic information.

Answer:

messenger RNA (mRNA)

Explanation:

The working copy of the DNA is called messenger RNA (mRNA). Its ready by  organelles such as ribosomes to manufacture amino acids to make proteins.

disorders of urinary system​

Answers

Answer:

Bladder infections - (cystitis) usually caused by bacteria.Enlarged prostate - in men, this can make it difficult to empty the bladder.Incontinence - when urine leaks out of the urethra.Kidney infections - when a bladder infection ‘backs up’ the ureters.Kidney stones - caused by infection and high blood levels of calcium.

Hope this helps

Yep I agree with the top answer. Diabetes is also kinda part of it but not really
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